Rabbit Polyclonal HMGCR antibody for IHC, WB. Published in 2 Pubmed References. Order anti-HMGCR antibody ABIN3022294.

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HMGCR antibody LS-C318764 is an HRP-conjugated rabbit polyclonal antibody to human HMGCR (HMG-CoA Reductase). Validated for ELISA, IHC and WB.

It is unclear whether anti‐HMGCR IgG antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are mainly associated with necrotizing autoimmune myopathy (NAM) in a subset of statin-treated patients. Although infrequent, these antibodies may also be observed in statin-naive patients with NAM. 2020-08-13 HMGCR : Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies 2020-01-08 HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples. Cat.No. 13533-1-AP. Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR () We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.

Hmgcr antibody

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2016-12-01 Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. HMGCR antibodies. HMGCR Antibody, Biotin conjugated ( ELISA ) ( CSB-PA010565LD01HU ) HMGCR Antibody, HRP conjugated ( ELISA ) ( CSB-PA010565LB01HU ) HMGCR Antibody, FITC conjugated ( ELISA ) ( CSB-PA010565LC01HU ) HMGCR Antibody ( ELISA,IHC ) ( CSB-PA031676 ) HMGCR Antibody ( ELISA,IHC ) ( CSB-PA929004 ) More>> HMGCR Proteins Select HMGCR antibodies from monoclonal antibodies listed below. View detailed HMGCR antibody specifications by linking to the specific product blocks. Select appropriate HMGCR antibodies for your research by isotype, epitope, applications and species reactivity. To the left of the product names in the table below, indicates those antibodies Cites: Anti-HMGCR Antibody (A1633) Abstract: miRNAs are involved in many physiologic and disease processes by virtue of degrading specific mRNAs or inhibiting their translation.

To the left of the product names in the table below, indicates those antibodies HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase) is a Protein Coding gene. Diseases associated with HMGCR include Familial Hyperlipidemia and Sitosterolemia. Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and Regulation of cholesterol biosynthesis by SREBP (SREBF).

HMGCR Antibodies Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels.

Probability of Not Meeting DOI. Aggarwal et al. A&R 2014  Transkriptnivåer av HMGCR minskade signifikant i HepG2, minskade obetydligt The primary antibody for ABCG1 was purchased from Abcam  We discovered that Hmgcr regulates carbohydrate-dependent feeding saliva samples and serum antibody responses during infection by SARS-CoV an  HMGCR antibody myositis presenting as limb girdle muscular dystrophy (oktober 2020) https://www.nmd-journal.com/article/S0960-8966(20)30491-0/abstract.

Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR). Polyclonal antibody preparation. Size: 100 ug. Reactivity: Rattus 

Hmgcr antibody

浓度: 1mg/ml. 保存条件: Summaries for HMGCR gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio Product Name: HMGCR antibody: Catalog Number: orb228653: Species/Host: Rabbit: Reactivity: Human, Mouse, Rat: Conjugation: Unconjugated: Tested applications: IHC-P, WB Rabbit recombinant monoclonal HMGCR antibody [EPR1685(N)]. Validated in WB, IP and tested in Mouse, Rat, Human. Cited in 53 publication(s). 343 products Anti-HMGCR antibodies are offered by a number of suppliers. This target gene encodes the protein '3-hydroxy-3-methylglutaryl-CoA reductase' in  HPA008338 Sigma-Aldrich. Anti-HMGCR antibody produced in rabbit.

Hmgcr antibody

quantity:  Rabbit Polyclonal HMGCR antibody. Validated in WB, ICC/IF, IHC-P. Tested in Human, Mouse, Rat. Cited in 1 reference(s). Mar 5, 2021 Complete information for HMGCR gene (Protein Coding), 3-Hydroxy-3- Methylglutaryl-CoA Reductase, including: function, proteins, disorders,  Feb 25, 2020 Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and antisignal recognition particle (SRP) antibodies are frequently associated  May 1, 2019 IgG antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are mainly associated with necrotizing autoimmune myopathy  ANTI-HMGCR ANTIBODIES. Test Code HMGCR ABS Alias/See Also 3-Hydroxy- 3-Methylglutaryl Coenzyme A Reductase (HMGCR) Antibody, IgG. BILL CODE:  Aug 14, 2018 The presence of anti-HMGCR antibodies, in conjunction with clinical findings and other laboratory tests, is an aid in the diagnosis of idiopathic  May 27, 2020 Anti-HMGCR autoantibodies can be used not only for diagnosis, but also as a marker of disease activity. The titers of the antibody are strongly  Aetna considers measurement of autoantibodies against 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase (anti-HMGCR antibody testing)   Dec 29, 2020 This indicates the importance of muscle biopsy and specific autoantibody testing for accurate diagnosis, as well as significant therapeutic  Useful For. Evaluating patients with suspected necrotizing autoimmune myopathy . Measuring 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies  1.
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Method Quanta Lite HMGCR ELISA.

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered  Anti-HMGCR antibody produced in rabbit (Anti-3-hydroxy-3-methylglutaryl-CoA reductase, LDLCQ3); ~ 1.0mg/mL, affinity isolated antibody; Suitable for western   Anti-HMGCR Polyclonal, Catalog # 13533-1-AP. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications.
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anti-HMGCR Antibody reacting with Rabbit and identified with ELISA, WB, IHC, IF . Quality is guaranteed.

Conclusions: Patients with HMGCR antibody–associated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology. Only a minority of patients with HMGCR antibody–associated myopathies have a history of statin exposure.


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View application images and datasheets for 163 anti HMGCR Antibody antibodies from 20 leading antibody suppliers, plus reviews and the top related antibodies

Antibodies against HMG-CoA reductase (HMGCR) are associated with necrotizing autoimmune-myopathy and can be detected in about 25% of these patients. Antibodies against HMGCR are associated with elevated levels of creatine kinase (CK) in blood. Pronounced proximal muscle weakness is typical while lung involvement is less common. A subset of immune-mediated necrotizing myositis, anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) myopathy is a rare disease that occurs in 0.9 to 1.4 cases per 100,000 people. It causes significant muscle weakness that does not resolve with discontinuation of the statin. Conclusions: Patients with HMGCR antibody–associated myopathies present with weakness and muscle discomfort and often have damage to both perimysial connective tissue and muscle fibers, with necrosis and myonuclear pathology. Only a minority of patients with HMGCR antibody–associated myopathies have a history of statin exposure.

HMGCR antibody LS-C318764 is an HRP-conjugated rabbit polyclonal antibody to human HMGCR (HMG-CoA Reductase). Validated for ELISA, IHC and WB.

Validated in WB, IP and tested in Mouse, Rat, Human. Cited in 53 publication(s).

The purpose of this study is to specify the characteristics at AINM diagnosis, treatments and evolution of juvenile AINM with anti-HMGCR or anti-SRP antibodies. Anti-HMGCR myopathy may resemble limb-girdle muscular dystrophy (2018) A case of juvenile HMGCR antibody myositis presenting as limb girdle muscular  RNA Polymerase-antikroppar [450] · KS antibodies (Asparaginyl-tRNA-Synthetase) KS-antikroppar (Asparaginyl-tRNA-Synthetase) [481] · HMGCR antibodies  HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the mevalonate pathway, is the target of statins. However, data on statin-induced effects on HMGCR  vid anti-HMGCR-positiv myopati. Orsaken till IMNM är med positiva anti-HMGCR antikroppar och nekrotiserande Antibody to signal recognition partic-. av A Miettinen — HMGCR-antikroppar cellular antigens referred to as anti-nuclear antibodies.